| Identification | Back Directory | [Name]
9-(3-hydroxyphenyl)-8-(4-methylphenyl)-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol | [CAS]
919010-46-1 | [Synonyms]
Pfn1INC1
Pfn1-IN-C1
Pfn1 IN C1
Pfn1 inhibitor C1
9-(3-hydroxyphenyl)-8-(4-methylphenyl)-4,9-dihydrotetraazolo[1',5':1,2]pyrimido[4,5-d]pyridazin-5-ol | [Molecular Formula]
C19H15N7O2 | [MOL File]
919010-46-1.mol | [Molecular Weight]
373.37 |
| Hazard Information | Back Directory | [Description]
Pfn1-IN-C1 is an inhibitor of Profilin1 (Pfn1). It has been shown to reduce the overall level of cellular filamentous (F)-actin, slow EC migration and proliferation, and inhibit the angiogenic ability of EC both in vitro and ex vivo. |
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