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ChemicalBook--->CAS DataBase List--->91037-75-1

91037-75-1

91037-75-1 Structure

91037-75-1 Structure
IdentificationBack Directory
[Name]

glycyl-arginyl-glycyl-aspartyl-seryl-proline
[CAS]

91037-75-1
[Synonyms]

glycyl-arginyl-glycyl-aspartyl-seryl-proline
Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline
L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-
[Molecular Formula]

C22H37N9O10
[MOL File]

91037-75-1.mol
[Molecular Weight]

587.58
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

GRGDSP is a synthetic linear RGD peptide that is an integrin inhibitor.
[in vitro]

It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly -Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization.

p>
[target]

Integrin

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