Identification | Back Directory | [Name]
PYRILAMINE | [CAS]
91-84-9 | [Synonyms]
Pyra rd2786 Parmal Dipane Histan Isamin rp2786 Stamine Stangen Kriptin Enrumay Coradon Nisaval Nyscaps RP 2786 Pyramal Mepyren Histasan Anhistol Antamine Anthisan Histacap Histalon Statomin Thylogen NSC13136 NSC-13136 NSC 13136 Maranhist Copsamine Afko-Hist Anhistabs Triaminic Harvamine Mepyramin R.d. 2786 Paraminyl Neo-Bridal Pyrilamide Mepyramine NCI-C60651 Antalergan Dorantamin Mepiramine Histapyran PYRILAMINE Antallergan Neoantergan Pyranisamine MEPYRAMINE BASE Pyrilamine base PYRILAMINE USP/EP/BP Pyrilamine(mepyramine) MEPYRAMINE(PYRILAMINE) MEPYRAMINE (PYRILAMINE) BASE Wait's Green mountain antihistamine Pyrilamine (base and/or unspecified salts) p-methoxybenzyl-alpha-pyridyl-dimethyl-aethylendiamin p-Methoxy-benzyl-alpha-pyridyl-dimethyl-aethylendiamin 2-dimethylaminoethyl-(4-methoxybenzyl)-(2-pyridyl)amine 2-((2-dimethylaminoethyl)(p-methoxybenzyl)amino)pyridine 2-((p-Methoxybenzyl)(2-(dimethylamino)ethyl)amino)pyridine 2-[[2-(Dimethylamino)ethyl](p-methoxybenzyl)amino]pyridine 2-((2-(dimethylamino)ethyl)(p-methoxybenzyl)amino)-pyridin 2-((2-(dimethylamino)ethyl)-(p-methoxybenzyl)amino)pyridine N-p-methoxybenzyl-N',N'-dimethyl-N-a-pyridylethylenediamine Pyridine, 2-((p-methoxybenzyl)(2-(dimethylamino)ethyl)amino)- Pyridine, 2-[[2-(dimethylamino)ethyl](p-methoxybenzyl)amino]- n-(p-methoxybenzyl)-n’,n’-dimethyl-n-2-pyridylethylenediamine N',N'-Dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-(pyridylethylene)diamine n-p-methoxybenzyl-n’,n’-dimethyl-n-alpha-pyridylethylenediamine N-(p-Methoxybenzyl)-N',N'-dimethyl-N-2-pyridyl-1,2-ethanediamine n-(para-methoxybenzyl)-n’,n’-dimethyl-n-2-pyridylethylenediamine N,N-Dimethyl-N'-(p-methoxybenzyl)-N'-(2 -Pyridyl)ethylenediamine n-para-methoxybenzyl-n’,n’-dimethyl-n-alpha-pyridylethylenediamine Ethylenediamine, N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)- N-(4-Methoxy-benzyl)-N,N-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine N-(p-Methoxybenzyl)-N',N'-dimethyl-N-(alpha-pyridyl)ethylenediamine N-Dimethylamino-aethyl-N-p-methoxy-benzyl-alpha-amino-pyridin-maleat N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(alpha-pyridyl)-ethylenediaminene N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine n-[(4-methoxyphenyl)methyl]-n’,n’-dimethyl-n-2-pyridinyl-1,2-ethanediamine 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridyl- N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-yl-ethane-1,2-diamine 1,2-Ethanediamine, N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-2-pyridinyl- 1,2-Ethanediamine, N1-[(4-methoxyphenyl)methyl]-N2,N2-dimethyl-N1-2-pyridinyl- | [EINECS(EC#)]
202-102-2 | [Molecular Formula]
C17H23N3O | [MDL Number]
MFCD00023451 | [MOL File]
91-84-9.mol | [Molecular Weight]
285.38 |
Chemical Properties | Back Directory | [Melting point ]
131-132 °C | [Boiling point ]
bp5 201°; bp0.06 168-172° | [density ]
1.0141 (rough estimate) | [refractive index ]
nD25 1.5760-1.5765 | [pka]
pKa 4.02(H2O
t=25
c=0.002 to 0.01) (Uncertain);8.92 (Uncertain) | [Water Solubility ]
3.425g/L(37.5 ºC) | [EPA Substance Registry System]
Mepyramine (91-84-9) |
Hazard Information | Back Directory | [Uses]
Antihistaminic. | [Uses]
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyridin-2-yl)ethane-1,2-diamine also known as pyrilamine works in synergism with diclofenac as a therapeutic alternative for clinical management of inflammatory pain. | [Uses]
Pyrilamine is also used for allergy symptoms and rhinitis. | [Definition]
ChEBI: An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group. | [Brand name]
Histavet-P [Veterinary] (Schering-Plough Animal Health); Pymafed (HoechstRoussel). | [Synthesis Reference(s)]
Journal of the American Chemical Society, 68, p. 1999, 1946 DOI: 10.1021/ja01214a037 | [General Description]
Viscous brown liquid. | [Air & Water Reactions]
May be sensitive to light. Insoluble in water. | [Reactivity Profile]
PYRILAMINE neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate flammable gaseous hydrogen in combination with strong reducing agents, such as hydrides. | [Health Hazard]
SYMPTOMS: Exposure to PYRILAMINE may cause somnolence, central nervous system depression and gastrointestinal disturbances. It may also cause drowsiness, dryness of the mouth, headache, nausea, tachycardia, urinary retention, nervousness, disorientation, staggering gait, hallucinations, stupor, coma, hyperflexia, tremors, excitement, nystagmus, hyperthermia, convulsions, agranulocytosis and aplastic anemia. | [Fire Hazard]
Flash point data for PYRILAMINE are not available; however, PYRILAMINE is probably combustible. |
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Company Name: |
Ralington Pharma
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Tel: |
+91-7948911722 +91-9687771722 |
Website: |
www.ralingtonpharma.com |
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