| Identification | Back Directory | [Name]
Inflachromene | [CAS]
908568-01-4 | [Synonyms]
Inflachromene
Inflachromene
(ICM)
5,12b-dihydro-10-hydroxy-7,7-dimethyl-2-phenyl-1H,7H-[1]benzopyrano[4,3-c][1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione | [Molecular Formula]
C21H19N3O4 | [MDL Number]
MFCD30719253 | [MOL File]
908568-01-4.mol | [Molecular Weight]
377.39 |
| Chemical Properties | Back Directory | [Boiling point ]
532.6±60.0 °C(Predicted) | [density ]
1.50±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF:30.0(Max Conc. mg/mL);79.49(Max Conc. mM)
DMSO:30.0(Max Conc. mg/mL);79.49(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.53(Max Conc. mM)
Ethanol:2.5(Max Conc. mg/mL);6.62(Max Conc. mM) | [form ]
A crystalline solid | [pka]
9.65±0.40(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
Inflachromene is a novel microglial inhibitor, which binds to HMGB1 (High Mobility Group Box 1) and HMGB2 (High mobility Group Box 2) inhibiting microglia-mediated neuroinflammation. |
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