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ChemicalBook--->CAS DataBase List--->9068-16-0

9068-16-0

9068-16-0 Structure

9068-16-0 Structure
IdentificationBack Directory
[Name]

PARG
[CAS]

9068-16-0
[Synonyms]

PARG
PARG human
EC 3.2.1.143
PARG (BOVINE)
FNDC5 (cleaved)
PARG IMMUNOBLOT STANDARD
POLY(ADP-RIBOSE) GLYCOHYDROLASE
Irisin, Recombinant, Human (Fibronectin Type III Domain-containing Protein 5, (cleaved)
[MDL Number]

MFCD02688310
Chemical PropertiesBack Directory
[storage temp. ]

-70°C
[form ]

liquid
[color ]

clear
[biological source]

human
[Water Solubility ]

water: soluble
Hazard InformationBack Directory
[Uses]

PARG human has been used in the digestion of sciatic nerve sections, in co-immunoprecipitation, in in vitro glycohydrolase activity assay
[Biological Activity]

Poly(ADP-ribose) glycohydrolase(PARG) hydrolyzes poly(ADP-ribose) at glycosidic(1μμ-2μμ) linkage of ribose-ribose bond to produce free ADP-ribose. It is an endo- and exo-glycosidase. PARG plays arole in DNA repair and replication. Inhibited or depleted PARG in cells aremore prone to DNA-damaging agents. PARG also averts the accumulation of PAR inthe cytoplasm and parthanatosa caspase-independent PAR-mediated type of celldeath.
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