| Identification | Back Directory | [Name]
FmocNH-PEG3-CH2CH2NH2 HCl | [CAS]
906079-91-2 | [Synonyms]
FmocNH-PEG3-CH2CH2NH2 HCl
Fmoc-PEG3-amine(HCl salt)
FmocNH-PEG3-CH2CH2NH2 hydrochloride | [Molecular Formula]
C23H31ClN2O5 | [MDL Number]
MFCD31656986 | [MOL File]
906079-91-2.mol | [Molecular Weight]
450.96 |
| Hazard Information | Back Directory | [Biological Activity]
FmocNH-PEG3-CH2CH2NH2 (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [References]
[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. |
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