| Identification | Back Directory | [Name]
3-Pyridinecarbonitrile, 5-fluoro-2-[[(1S)-1-(4-fluorophenyl)ethyl]amino]-6-[[5-(1-methylethoxy)-1H-pyrazol-3-yl]amino]- | [CAS]
905585-60-6 | [Synonyms]
3-Pyridinecarbonitrile, 5-fluoro-2-[[(1S)-1-(4-fluorophenyl)ethyl]amino]-6-[[5-(1-methylethoxy)-1H-pyrazol-3-yl]amino]- | [Molecular Formula]
C20H20F2N6O | [MOL File]
905585-60-6.mol | [Molecular Weight]
398.41 |
| Hazard Information | Back Directory | [Description]
AZD6918 is a novel potent and selective inhibitor of the Trk tyrosine kinases. AZD-6918 attenuates the BDNF/TrkB-induced protection of neuroblastoma cells from etoposide in vitro and in vivo. AZD6918 inhibited wild-type TrkB-induced cell migration and cell growth. |
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