| Identification | Back Directory | [Name]
PHOSPHODIESTERASE I | [CAS]
9025-82-5 | [Synonyms]
EC 3.1.4.1
Power phos
IUB: 3.1.4.1
5'-EXONUCLEASE
EC 3.1.4.1 TYPE V
VENOM EXONUCLEASE
EC 3.1.4.1 TYPE IV
phosphodiesterases
EC 3.1.4.1 TYPE VI
PHOSPHODIESTERASE I
5'-EXONUCLEASE TYPE V
5'-phosphodiesterases
5'-EXONUCLEASE TYPE VI
5'-EXONUCLEASE TYPE IV
PHOSPHODIESTERASE I TYPE V
PHOSPHODIESTERASE I TYPE VI
PHOSPHODIESTERASE I TYPE IV
PHOSPHODIESTERASE I USP/EP/BP
OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE
Phosphodiesteraseifromcrotalusadamanteus
Native Bothrops atrox Phosphodiesterase I
PHOSPHODIESTERASE (FROM CROTALUS DURISSUS)
Phosphodiesterase I from Bothrops atrox
OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE TYPE V
OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE TYPE VI
OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE TYPE IV
PHOSPHODIESTERASE I TYPE V FROM*BOTHROPS ATROX
phosphodiesterase I type vii*from crotalus atrox
phosphodiesterase I from bovine*intestinal mucosa
phosphodiesterase i from crotalus adamanteus venom
PUTRESCINE DIHYDROCHLORIDE PLANT CELL*CU LTURE TESTE
Native Crotalus adamanteus venom Phosphodiesterase I
5μ-Exonuclease, Oligonucleate 5μ-nucleotidohydrolase
Phosphodiesterase I From Crotalus Adamanteus Venom BR,20U/mg
Native Crotalus atrox (Western Diamondback Rattlesnake) Phosphodiesterase I
Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake)
Phosphodiesterase I from Crotalus adamanteus venom,5′-Exonuclease, Oligonucleate 5′-nucleotidohydrolase | [EINECS(EC#)]
232-806-5 | [Molecular Formula]
NULL | [MDL Number]
MFCD00131883 |
| Hazard Information | Back Directory | [Description]
The food enzyme phosphodiesterase I (oligonucleotide 5′‐nucleotidohydrolase; EC 3.1.4.1) is produced with the non‐genetically modified Leptographium procerum strain FDA by DSM Food Specialties B.V. The food enzyme is free from viable cells of the production organism. It is intended to be used to process yeast and yeast products. Phosphodiesterase I exhibits phosphohydrolase activity against NAD, nucleoside diphosphate sugars, and nucleoside tniphosphates. The enzyme was first isolated from rattlesnake venom and has been the subject of several reviews. Razzell partially purified a mammalian PDE I from a porcine kidney, and subsequent cell fractionation studies by other workers demonstrated the enzyme in the plasma membrane of rat liver cells[1-2].
| [References]
[1] D J Morley. “Distribution of phosphodiesterase I in normal human tissues.” Journal of Histochemistry & Cytochemistry 35 1 (1987): 75–82.
[2] on Food Contact Materials, EFSA Panel Enzymes and Processing Aids (CEP). “Safety evaluation of the food enzyme phosphodiesterase I from the non-genetically modified Leptographium procerum strain FDA.” EFSA Journal 22 4 (2024). | [Uses]
Phosphodiesterase (PDE) is any enzyme that is used to breaks phosphodiester bonds. It is a membrane-bound glycoprotein that is used to catalyze the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is used in phosphodiesterase activation assays to hydrolyze AMP. | [Biochem/physiol Actions]
Phosphodiesterase I breaks phosphodiester bonds and catalyzes the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is released from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C. |
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