Identification | Back Directory | [Name]
OCTYLPHENYLPOLYETHYLENE GLYCOL | [CAS]
9002-93-1 | [Synonyms]
tx100 NP 40 X-305 X-405 tritonx hydrolsw LISSAPOL preceptin Octoxinol tritonx101 tritonx102 tritonx165 tritonx305 tritonx705 Trion X-100 Triton X 100 TRITON X-155 TRITON DF-20 antaroxa-200 texoforfp300 NONIDET P 40 OCTOXYNOL-12 OCTOXYNOL-13 OCTOXYNOL-16 OCTOXYNOL-20 OCTOXYNOL-25 OCTOXYNOL-30 OCTOXYNOL-33 OCTOXYNOL-40 OCTOXYNOL-70 SYNPERONIC N TERGITOL NP-9 TERGITOL NO 4 TERGITOL NP-7 NONIDET NP-40 IMBENTIN-N/52 IGEPAL CO-630 IGEPAL CA 630 TRITON 15-S-7 JGEPAL CA-630 SYNPERONIC NX TRITON 15-S-9 Triton X-100T Triton X100kg Trypsin2000U/G TERGITOL NP 40 TERGITOL NP 27 EmulsifierTX-10 OP-4 Emulsifier OP-10 Emulsifier Triton\(rg X-100 TRIFLURALIN NEAT IGEPAL(R) CO-630 NP-40 SUBSTITUTE SYNPERONIC NP 10 SYNPERONIC NP 30 TRITONX-100(BULK Emulsifier OP-10 TERGITOL(TM) NP-4 TERGITOL(R) NP-40 TERGITOL(TM) NP-8 TERGITOL(TM) NP-9 TERGITOL(TM) NP-6 TERGITOL(TM) NP-7 NP-40 ALTERNATIVE EPA604-PHENOL MIX Triton X-100 250ML Triton X-114 500ML NP40- NONIDET P-40 TERGITOL(TM) NP-40 TERGITOL(TM) NP-10 TRITON X-100 X-405 triton x-100solution triton x-165solution triton x-305solution triton x-405solution POE (15) NONYLPHENOL Octoxynol 9 (200 mg) OCTYLPHENYLPOLYETHYL TRITON X-100, 100 ML Triton X-100 (n=4-17) triton x-405 solution TRITON X-100, REDUCED NONIDET P40 SUBSTITUTE octylphenoxypolyethoxy TRITON(R) N-101 REDUCED triton x-705-70solution TRITON(R) X-100 BIOXTRA 1,3-Dicaprinoylglycerol Triton X-100, extra pure TRITON(R) X-405 SOLUTION TRITON X-100, SIGMAULTRA ETHOXYLATED ALKYL PHENOL NONIDET(R) P 40 SUBSTITUTE POLYOXYETHYLENEOCTYLPHENOL POLYOXYETHYLENEOXTYLPHENOL Triton(R) X-100 solution Triton(R) X-165 solution Triton(R) X-305 solution TRITON X-114, REAGENT GRADE TERGITOL(TM) TP-9(NONIONIC) POLYOXYETHYLENE OCTYL PHENYL TERGITOL(TM) NP-40(NONIONIC) TERGITOL(TM) NP-27(NONIONIC) TERGITOL(TM) NP-33(NONIONIC) ethoxylatedp-tert-octylphenol TritonX-100ScintillationGrade Triton(R) X-705-70 solution OCTYLPHENYLPOLYETHYLENE GLYCOL NONYLPHENYL POLYETHYLENE GLYCOL Polyethylene glycol octylphenyl Triton X-405, 70% solution in H2O polyethyleneglycoloctylphenolether POLYOXYETHYLENE(9)NONYLPHENYL ETHER Triton(R) X-100,scintillation grade TRITON X-100 FOR GAS CHROMATOGRAPHY TRITON X-405, 70% SOLUTION IN WATER Octylphenol polyoxyethylene ether Triton X-100, for Molecular biology TRITON(R) X-100 SOLUTION, FOR MOLECU tert-Octylphenoxy polyethoxylethanol IGEPAL CA-630 MOLECULAR BIOLOGY GRAD TRITON X-100 MOLECULAR BIOLOGY REAGE ELECTROPHORESIS REAGENT TRITON X-100 TRITON X-100 NF PHARMACEUTICAL GRADE TRITON X-100 (OCTYLPHENOL ETHOXYLATE) polyethyleneglycol-(tert-octyl)phenyl POLYOXYETHYLENE(20) NONYLPHENYL ETHER POLYETHYLENE GLYCOL NONYLPHENYL ETHER POLYOXYETHYLENE(15) NONYLPHENYL ETHER POLYOXYETHYLENE(18) NONYLPHENYL ETHER Triton(r) x-405, 70% solution in water TRITON X-100 MOLECULAR BIOLOGY REAGENT TRITON(R) X-100, FOR MOLECULAR BIOLOGY NINHYDRIN REAGENT 2X1L BUFFER/REAGENTS p-Octylphenylpolyethylene glycol ether Triton X-705-70 solution, 70% in water TRITON(R) X-100 SOLUTION, ~10% IN WATER Triton X-405, 70% solution in water 1LT TRITON(R) X-305 SOLUTION, ~70% IN WATER TRITON(R) X-165 SOLUTION, ~70% IN WATER PARA-TERT-OCTYLPHENOXYNONAETHOXY-ETHANOL Triton(TM) X-100 Vetec(TM) reagent grade Triton X-405, 70% solution in water 2.5LT 9-Polyethyleneglycoltert-octylphenylether Polyethylene glycol tert-octylphenyl ether tert-Octylphenoxy poly(oxyethylene)ethanol IGEPAL CA-210 .IGEPAL CA-520.IGEPAL CA-720 TRITON(R) X-705-70 SOLUTION, ~70% IN WAT ER Triton(R) X-100 for scintillation techniques POLYOXYETHYLENE (12) NORMAL-OCTYLPHENYL ETHER -[(1, 1, 3, 3-TetraMethylbutyl) phenyl]-oMega POLYOXYETHYLENE BRANCHED NONYLCYCLOHEXYL ETHER polyethyleneglycoloctylphenolether(tritonx-100) NONYLPHENOXY POLY(ETHYLENEOXY)ETHANOL, BRANCHED Marlophen 87p-Isooctylphenoxypolyethoxyethanol α-[(1,1,3,3-TetraMethylbutyl) phenyl]-ω-hydroxy Octylphenoxy poly(ethyleneoxy)ethanol, branched Triton X 100 (Trademark of Union Carbide Company) Polyethylene Glycol Mono-4-octylphenyl Ether  ProteinSolubilizerX-100,ReadytouseAmpules,Sterile Polyethylene Glycol Mono-4-octylphenyl Ether n(=:)10 TRITON X-100 SCINTILLATIONTECHNIQUES ANALYTICAL GRADE polyethyleneglycolp-1,1,3,3-tetramethylbutylphenylether Triton X-100: (Poly(oxyethylene)-p-tert-octylphenyl ether) TRITON(R) X-100 SOLUTION, FOR MOLECULAR BIOL. ~10% IN WATER Polyethylene Glycol Mono-4-octylphenyl Ether (n=approx. 10) Olyethyleneglycolmono(p-1,1,3,3-tetramethylbutyl)phenylether TRITON(R) X-100 SOLUTION, ~10% IN WATER, PGE W. 6X10ML VIALS 4-(1,1,3,3-tetramethylbutyl)phenyl-polyethylene glycol solution Polyethylene glycol tert-octylphenyl ether [70% solution in water] glycols,polyethylene,mono(p-(1,1,3,3-tetramethylbutyl)phenyl)ether Polyethylene Glycol Mono-4-octylphenyl Ether n(=:)10(Triton X-100) Triton X 100 pharm. grade (Trademark of Union Carbide Company) Triton? X-100, For molecular biology, DNAse, RNAse and Protease free Triton(R) X-100,98%,for molecular biology,DNAse,RNAse and Protease free Triton X-100, 98%, for Molecular biology, DNAse, RNAse and Protease free Triton X-100, DNAse, RNAse and Protease free, for molecular biology, 98% poly(oxy-1,2-ethanediyl),alpha-(4-(1,1,3,3-tetramethylbutyl)phenyl)-omega-hy poly(oxy-1,2-ethanediyl),alpha-[4-(1,1,3,3-tetramethylbutyl)phenyl]-omega-hy Triton X-100, DNAse, RNAse and Protease free, for Molecular biology, 98% 100ML Poly(oxy-1,2-ethanediyl), alpha-[4-(1,1,3,3-tetramethylbutyl) phenyl-\o-hydroxy Polyethylene Glycol Mono-4-octylphenyl Ether n(=:)10 [for Biochemical Research] Triton(r) X-100, 98%, dnase, rnase and protease free, peroxides free, for molecular Poly(oxy-1,2-ethanediyl), .alpha.-4-(1,1,3,3-tetramethylbutyl)phenyl-.omega.-hydroxy- 2-ethanediyl),.alpha.-(4-(1,1,3,3-tetramethylbutyl)phenyl)-.omega.-hydroxy-Poly(oxy-1 Polyethylene Glycol Mono-4-octylphenyl Ether (n=approx. 10) [for Biochemical Research] Triton X-100, DNAse, RNAse and Protease free, peroxides free, for molecular biology, 98% Polyethylene glycol tert-octylphenyl ether, Polyoxyethylene (40) isooctylphenyl ether 4-(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol, Polyethylene glycol 4-tert-octylphenyl ether Triton X-45,4-(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol, Polyethylene glycol 4-tert-octylphenyl ether 4-(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol, t-Octylphenoxypolyethoxyethanol, Polyethylene glycol tert-octylphenyl ether Triton X-100,4-(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol, t-Octylphenoxypolyethoxyethanol, Polyethylene glycol tert-octylphenyl ether | [EINECS(EC#)]
255-695-5 | [Molecular Formula]
C18H28O5 | [MDL Number]
MFCD00132851 | [MOL File]
9002-93-1.mol | [Molecular Weight]
324.412 |
Chemical Properties | Back Directory | [Appearance]
clear viscous liquid | [Melting point ]
44-46 °C
| [Boiling point ]
250 °C(lit.)
| [density ]
1.06 g/mL at 20 °C
| [vapor density ]
>1 (vs air) | [vapor pressure ]
< 1.33 hPa at 20 °C | [refractive index ]
n20/D 1.491
| [Fp ]
535 °F
| [storage temp. ]
2-8°C
| [solubility ]
H2O: 0.005 M at 20 °C, clear, colorless
| [form ]
Viscous Liquid | [color ]
≤100(APHA)
| [Odor]
Odorless | [PH]
6.5-8.5 (25℃) | [PH Range]
9.7 | [Water Solubility ]
Miscible with water. | [Merck ]
14,6761 | [BRN ]
2315025 | [LogP]
4.610 (est) | [EPA Substance Registry System]
Octoxynol 9 (9002-93-1) |
Hazard Information | Back Directory | [Chemical Properties]
clear to slightly hazy liquid | [Definition]
ChEBI: A poly(ethylene glycol) terminated with a 4-(2,4,4-trimethylpentan-3-yl) phenyl group at one end. | [Uses]
Nonionic detergent, emulsifier, dispersing agent. Octoxynol-9 as spermaticide. | [Description]
Triton X-100(9002-93-1) is a nonionic surfactant that has a hydrophilic polyethylene oxide chain (on average it has 9.5 ethylene oxide units) and an aromatic hydrocarbon lipophilic or hydrophobic group. The hydrocarbon group is a 4-(1,1,3,3-tetramethylbutyl)-phenyl group. Triton X-100 is closely related to IGEPAL CA-630 or former Nonidet P-40, which might differ from it mainly in having slightly shorter ethylene oxide chains. Thus Triton X-100 is slightly more hydrophilic than Igepal CA-630; these two detergents may not be considered to be functionally interchangeable for most applications. Triton X-100 is a common non-ionic surfactant and emulsifier which is often used in biochemical applications to solubilize proteins. It is considered a comparatively mild detergent, non-denaturing, and is reported in numerous references as a routinely added reagent. It is utilized for lysing cells to extract protein and cellular organelles. It can also permeabilize the living cell membrane for transfection.
| [Brand name]
Triton X-100 (Union Carbide). | [General Description]
Triton X-305 is a non-ionic surfactant. This octylphenol ethoxylate has higher number of ethylene oxide units, increased cmc (Critical micelle concentration) and hydrophile/lipophile balance when compared to Triton X-100. Triton X-305 is compatible with anionic, cationic, and other nonionic surfactants and chemically stable in most acidic and alkaline solutions. Triton X-100 is a nonionic detergent, 100% active ingredient, which is often used in biochemical applications to solubilize proteins. Triton X-100 has no antimicrobial properties. It is considered a comparatively mild detergent, non-denaturing, and is reported in numerous references as a routinely added reagent. It does absorb in the ultraviolet region of the spectrum, however, so can interfere with protein quantitation. A number of polymeric resins have been used to remove X-100 from solution, including Amberlite hydrophobic XAD resins and Rezorian A161 cartridges. The "X" series of Triton detergents are produced from octylphenol polymerized with ethylene oxide. The number ("-100") relates only indirectly to the number of ethylene oxide units in the structure. X100 has an "average of 9.5" ethylene oxide units per molecule, with an average molecular weight of 625. In addition, lower and higher mole adducts will be present in lesser amounts, varying slightly within supplier's standard manufacturing conditions. No antioxidants are added by Sigma or the manufacturer, but commercial preparations of Triton X-100 have been found to contain peroxides up to 0.22% hydrogen peroxide (H2O2) equivalents. These impurities may interfere with biological reactions. Sigma offers X-100-PC and X-100R-PC as biological grade alternatives. | [Hazard]
Triton X-100 is irritating to human skin and eyes, harmful if ingested and acutely toxic. It caused an increase in cellular and humoral immune responses in a 3-day intermittent skin study in mice, but there was no evidence of teratogenicity in rats. | [Biological Activity]
Triton X-100(9002-93-1) causes a change in the fluorescence characteristics of the Tritoln X-100 effectively ruptures chloroplasts and reduces the electron flow required for the Hill reaction at low concentrations. Treatment of pea root cell preparations with Tritoln X-100 and low-speed centrifugation resulted in a pellet containing a large amount of stromal material (including RNA polymerase and DNA polymerase activity, most of the DNA, about 30% of the RNA, and 50% of the protein)[1-2].
| [Toxics Screening Level]
The current ITSL for Triton X-100 is 0.15 μg/m3, with annual averaging time (AT). | [References]
[1] L P VERNON; E S. Photochemical Activities of Spinach Chloroplasts Following Treatment with the Detergent Triton X-100.[J]. Plant Physiology, 1965. DOI:10.1104/pp.40.6.1269. [2] BOTTOMLEY W. Some effects of triton x-100 on pea etioplasts.[J]. Plant Physiology, 1970. DOI:10.1104/pp.46.3.437.
|
Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn,N | [Risk Statements ]
41-36/38-22-51/53-36-36/37/38-37/38-52/53 | [Safety Statements ]
26-39-36-61-36/39-36/37/39 | [RIDADR ]
UN 3082 9/PG 3
| [WGK Germany ]
3
| [RTECS ]
WZ4750000
| [F ]
3 | [TSCA ]
Yes | [HazardClass ]
9 | [PackingGroup ]
III | [HS Code ]
34021300 | [Safety Profile]
Moderately toxic by
ingestion and intravenous routes.
Experimental reproductive effects. Human
mutation data reported. An eye and human
skin irritant. Many glycol ethers cause
dangerous human reproductive effects.
When heated to decomposition it emits
toxic fumes of NOx. A surfactant. See also
GLYCOL ETHERS. | [Toxicity]
LD50 oral in rat: 1800mg/kg |
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