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ChemicalBook--->CAS DataBase List--->890129-26-7

890129-26-7

890129-26-7 Structure

890129-26-7 Structure
IdentificationBack Directory
[Name]

BGG463
[CAS]

890129-26-7
[Synonyms]

BGG463
K 0859
CS-2570
K 03859
BGG 463;BGG-463
BGG463 (K03859)
6-(6-acetamidopyrimidin-4-yl)oxy-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide
[Molecular Formula]

C30H29F3N6O3
[MDL Number]

MFCD31618015
[MOL File]

890129-26-7.mol
[Molecular Weight]

578.58
Chemical PropertiesBack Directory
[Boiling point ]

669.0±55.0 °C(Predicted)
[density ]

1.366±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : ≥ 125 mg/mL (216.05 mM)
[form ]

Solid
[pka]

12.06±0.70(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Biological Activity]

BGG463 (K03859) is an orally active inhibitor of type II CDK2.
[in vitro]

BGG463 potently inhibits T315I BCR–ABL autophosphorylation and shows good oral efficacy in mouse models of CML.

[target]

CDK2

[storage]

Store at -20°C
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