| Identification | Back Directory | [Name]
BenzaMide, 3-Methoxy-N-[3-(1-Methyl-1H-pyrazol-5-yl)-4-[2-(4-Morpholinyl)ethoxy]phenyl]- | [CAS]
887936-68-7 | [Synonyms]
APD791
Temanogrel
3-Methoxy-N-[3-(1-methyl-1H-pyrazol-5-yl)-4-[2-(4-morpholinyl)ethoxy]phenyl]benzamide
BenzaMide, 3-Methoxy-N-[3-(1-Methyl-1H-pyrazol-5-yl)-4-[2-(4-Morpholinyl)ethoxy]phenyl]-
inhibit,Temanogrel,Serotonin Receptor,5-HT Receptor,APD 791,APD-791,Inhibitor,5-hydroxytryptamine Receptor | [Molecular Formula]
C24H28N4O4 | [MDL Number]
MFCD18206792 | [MOL File]
887936-68-7.mol | [Molecular Weight]
436.5 |
| Chemical Properties | Back Directory | [Boiling point ]
556.4±50.0 °C(Predicted) | [density ]
1.24±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (286.37 mM) | [form ]
Solid | [pka]
12.88±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Temanogrel, is a highly selective 5-HT2A receptor antagonist with a Ki of 4.9 nM. Temanogrel also inhibits inositol phosphate accumulation with an IC50 of 5.2 nM. Temanogrel exhibits potent inhibition of serotonin mediated amplification of ADP-stimulated human and dog platelet aggregation (IC50=8.7 and 23.1 nM, respectively | [Definition]
ChEBI: Temanogrel is a member of benzamides. |
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