| Identification | Back Directory | [Name]
2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)- | [CAS]
875787-07-8 | [Synonyms]
LXR623
CS-758
WAY 252623
LXR623/LXR-623
LXR-623 (WAY-252623)
WAY-252623;LXR623;LXR 623;WAY252623;WAY 252623
2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
2H-Indazole, 2-[(2-chloro-4-fluorophenyl)Methyl]-3-(4-fluorophenyl)-7-(trifluoroMethyl)-
2-[(2-Chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole WAY 252623 | [Molecular Formula]
C21H12ClF5N2 | [MDL Number]
MFCD16495812 | [MOL File]
875787-07-8.mol | [Molecular Weight]
422.78 |
| Chemical Properties | Back Directory | [Melting point ]
93℃ | [Boiling point ]
528.4±50.0 °C(Predicted) | [density ]
1.40 | [storage temp. ]
room temp | [solubility ]
DMSO:50.0(Max Conc. mg/mL);118.26(Max Conc. mM)
Ethanol:52.0(Max Conc. mg/mL);123.0(Max Conc. mM) | [form ]
powder | [pka]
-1.87±0.30(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
WAY 252623 is a novel and potent LXR (liverX receptor) β-agonist used as a potential candidate for the treatment of atopic dermatitis. | [Biochem/physiol Actions]
WAY-252623 (LXR623) is an orally available, potent and highly selective Liver X receptors (LXRs) agonist that significantly reduced total and LDL-cholesterol. WAY-252623 reduces lesion progression in the murine LDLR(-/-) atherosclerosis model. | [storage]
Store at -20°C |
|
|