Identification | Back Directory | [Name]
1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE | [CAS]
869497-75-6 | [Synonyms]
VUF 6002 VUF6002 maleate VUF 6002 maleate JNJ 10191584 MALEATE JNJ 10191584 maleate salt 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE | [Molecular Formula]
C17H19ClN4O5 | [MDL Number]
MFCD08703121 | [MOL File]
869497-75-6.mol | [Molecular Weight]
394.81 |
Hazard Information | Back Directory | [Uses]
A highly selective histamine H4 receptor silent antagonist | [Biological Activity]
Highly selective histamine H 4 receptor silent antagonist; binds with high affinity to the human H 4 receptor (K i = 26 nM) and is > 540-fold selective over the H 3 receptor (K i = 14.1 μ M). In vitro, inhibits mast cell and eosinophil chemotaxis with IC 50 values of 138 and 530 nM respectively. Orally active in vivo . | [storage]
room temperature (desiccate) |
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
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