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ChemicalBook--->CAS DataBase List--->86770-75-4

86770-75-4

86770-75-4 Structure

86770-75-4 Structure
IdentificationBack Directory
[Name]

2-(Benzyloxyethoxyethoxy)ethylaMine
[CAS]

86770-75-4
[Synonyms]

CAS_86770-75-4
Benzyl-PEG3-NH2
H2N-(CH2CH2O)3-Bn
Benzyl-PEG3-amine
BnO-PEG2-CH2CH2NH2
2-[2-(2-Benzyloxy-ethoxy)-ethoxy
2-(Benzyloxyethoxyethoxy)ethylaMine
2-(2-(2-(benzyloxy)ethoxy)ethoxy)ethanamine
[Molecular Formula]

C13H21NO3
[MDL Number]

MFCD22383750
[MOL File]

86770-75-4.mol
[Molecular Weight]

239.31
Chemical PropertiesBack Directory
[Boiling point ]

348.7±27.0 °C(Predicted)
[density ]

1.051±0.06 g/cm3(Predicted)
[pka]

8.74±0.10(Predicted)
Hazard InformationBack Directory
[Biological Activity]

Benzyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
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