| Identification | Back Directory | [Name]
Dimethylenastron | [CAS]
863774-58-7 | [Synonyms]
enastron
Dimethylenastron
Eg5 Inhibitor III
Eg5 Inhibitor III(Dimethylenastron)
Dimethylenastron - Eg5 inhibitor III
Eg5 Inhibitor III, Dimethylenastron - CAS 863774-58-7 - Calbiochem
2,3,4,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-5(1H)-quinazolinone
4-(3-Hydroxyphenyl)-7,7-dimethyl-2-thioxo-2,3,4,6,7,8-hexahydroquinazolin-5(1H)-one
5(1H)-Quinazolinone, 2,3,4,6,7,8-hexahydro-4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo- | [Molecular Formula]
C16H18N2O2S | [MDL Number]
MFCD09264157 | [MOL File]
863774-58-7.mol | [Molecular Weight]
302.39 |
| Chemical Properties | Back Directory | [Boiling point ]
475.6±55.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble15mg/mL, clear | [form ]
powder | [pka]
9.59±0.10(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
Dimethylnasetron is an inhibitor of mitotic motor kinesin Eg5, triggering apoptosis and upregulates Hsp-70 in human myeloma cells. | [Biochem/physiol Actions]
Dimethylenastron is specific, reversible inhibitor of the mitotic motor kinesin Eg5. Dimethylenastron inhibits bipolar spindle formation, and inhibits proliferation, migration and invasion of several pancreatic cancer cell lines in cell based assays. | [storage]
Store at -20°C |
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TCI Europe
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| Company Name: |
TCI AMERICA
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800-4238616 |
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