Identification | Back Directory | [Name]
Pravastatin Lactone | [CAS]
85956-22-5 | [Synonyms]
R 414 SQ 31369 Pravastatin IMpurity D PRAVASTATIN SODIUM(RG) Pravastatin class ester Pravastatin EP IMpurity D (1S)-1β-[2-[[(2R,4R)-3,4,5,6-Tetrahydro-4β-hydroxy-6-oxo-2H-pyran]-2-yl]ethyl]-1,2,6,7,8,8aβ-hexahydro-2β-methyl-8α-[[(S)-2-methyl-1-oxobutyl]oxy]naphthalen-6β-ol (2S)-2-Methyl-Butanoic Acid (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester | [Molecular Formula]
C23H34O6 | [MDL Number]
MFCD06410952 | [MOL File]
85956-22-5.mol | [Molecular Weight]
406.51 |
Chemical Properties | Back Directory | [Appearance]
White Crystalline Powder | [Melting point ]
140-143°C | [Boiling point ]
590.5±50.0 °C(Predicted) | [density ]
1.18±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20?C Freezer, Under Inert Atmosphere | [solubility ]
DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 12.5 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [pka]
13.49±0.40(Predicted) | [Stability:]
Hygroscopic | [CAS DataBase Reference]
85956-22-5 |
Hazard Information | Back Directory | [Chemical Properties]
White Crystalline Powder | [Uses]
lipid-lowering drugs | [Uses]
Pravastatin Lactone is a metabolite of Pravastatin (P702000). | [Definition]
ChEBI: Pravastatin lactone is a delta-lactone, a fatty acid ester, a member of hexahydronaphthalenes and a polyketide. It is functionally related to a mevastatin and a (S)-2-methylbutyric acid. | [storage]
Store at -20°C |
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