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ChemicalBook--->CAS DataBase List--->858345-57-0

858345-57-0

858345-57-0 Structure

858345-57-0 Structure
IdentificationBack Directory
[Name]

Salvinorin A Carbamate
[CAS]

858345-57-0
[Synonyms]

Salvinorin A Carbamate
[Molecular Formula]

C22H27NO8
[MOL File]

858345-57-0.mol
[Molecular Weight]

433.45
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Acetonitrile: 1 mg/ml; DMF: 1 mg/ml; DMSO: 2 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
[form ]

A crystalline solid
Hazard InformationBack Directory
[Description]

Salvinorin A carbamate is a potent κ-opioid receptor (KOR) full agonist that is almost as potent as salvinorin A with EC50 values of 6.2 and 4.5 nM, respectively, for activation of the human KOR to enhance binding of [35S]GTPγS. The addition of a carbamate group to salvinorin A increases biological stability by decreasing deacetylation.
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