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ChemicalBook--->CAS DataBase List--->858102-79-1

858102-79-1

858102-79-1 Structure

858102-79-1 Structure
IdentificationBack Directory
[Name]

rolapitant hydrochloride (anhydrous)
[CAS]

858102-79-1
[Synonyms]

rolapitant hydrochloride (anhydrous)
[Molecular Formula]

C25H27ClF6N2O2
[MDL Number]

MFCD22572774
[MOL File]

858102-79-1.mol
[Molecular Weight]

536.937
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

Rolapitant is an NK1 receptor antagonist that is used in the treatment of chemotherapy-induced nausea and vomiting.
[Definition]

ChEBI: Rolapitant hydrochloride (anhydrous) is a hydrochloride obtained by combining irinotecan with one molar equivalent of hydrochloric acid. Used (in the form of the hydrate) for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy. It has a role as an antiemetic and a neurokinin-1 receptor antagonist. It contains a rolapitant(1+).
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