Identification | Back Directory | [Name]
Atrial Natriuretic Factor | [CAS]
85637-73-6 | [Synonyms]
ANP PND NPPA ATFB6 CDD-ANF Anti-ANP Anti-PND Atriopeptin Prepronatriodilatin PubChem ID: 16129708 natriuretic peptide A Atrial Natriuretic Factor Atrial natriuretic peptid Cardiodilatin-related peptide Atrial Natriuretic Peptide EIA Kit Anti-NPPA antibody produced in rabbit ANTI-NPPA (N-TERM) antibody produced in rabbit Anti-NPPA (C-terminal) antibody produced in goat | [Molecular Formula]
C127H203N45O39S3 | [MOL File]
85637-73-6.mol | [Molecular Weight]
3080.44 |
Hazard Information | Back Directory | [Uses]
For research use only. Not for use in diagnostic procedures. Atrial Natriuretic Peptide EIA Kit has been used to measure ANP levels in diabetes mellitus patients. | [Definition]
ChEBI: Carperitide is a polypeptide. | [General Description]
The ANP Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting ANP peptide based on the principle of Competitive Enzyme Immunoassay. EIA-ANP-1 targets the common sequence of human, mouse and rat, and thus may be used to detect ANP expression in all these species with high specificity and sensitivity. | [Biochem/physiol Actions]
Atrial natriuretic peptide (ANP) is a polypeptide hormone released in response to atrial dilation and it stimulates diuresis, natriuresis and vasorelaxation. ANP acts as an inhibitor of renin-angiotensin-aldosterone system (RAAS) pathway. It also has a major role in body fluid homeostasis and maintenance of blood pressure. Binding of ANP to receptors on target cell stimulate the production of cyclic guanosine monophosphate (GMP). Overexpression of ANP leads to congestive heart failure in the human. Experimental studies show that ANP can be used as a therapeutic for stimulating angiogenesis in ischemic tissues. N-terminal ANP prohormone functions as a biomarker for asymptomatic systolic left ventricular (LV) dysfunction, congestive heart failure and cardiovascular mortality. |
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M. H. K. Purse & Belts
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