| Identification | Back Directory | [Name]
4-Oxazolecarboxamide, 2-[[[3,4,5,6,7,8-hexahydro-4-oxo-3-(phenylmethyl)[1]benzothieno[2,3-d]pyrimidin-2-yl]thio]methyl]-N-[2-(1-pyrrolidinyl)ethyl]- | [CAS]
853136-76-2 | [Synonyms]
DK149
DK-1-49
DK 1 49
4-Oxazolecarboxamide, 2-[[[3,4,5,6,7,8-hexahydro-4-oxo-3-(phenylmethyl)[1]benzothieno[2,3-d]pyrimidin-2-yl]thio]methyl]-N-[2-(1-pyrrolidinyl)ethyl]- | [Molecular Formula]
C28H31N5O3S2 | [MOL File]
853136-76-2.mol | [Molecular Weight]
549.71 |
| Hazard Information | Back Directory | [Description]
DK-1-49 is an autophagonizer. DK-1-49 causes accumulation of autophagy-associated LC3-II and enhanced levels of autophagosomes and acidic vacuoles. Furthermore, cell viability is inhibited by autophagic cell death in not only human cancer cells but also Bax/Bak double-knockout cells. |
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