| Identification | Back Directory | [Name]
GKA-50 | [CAS]
851884-87-2 | [Synonyms]
GKA50
GKA-50
GKA 50
GKA-50; GKA 50
OCBMECSFDVUYQN-ROUUACIJSA-N
6-[[3-[(1S)-2-Methoxy-1-Methylethoxy]-5-[(1S)-1-Methyl-2-phenylethoxy]benzoyl]aMino]-3-pyridinecarboxylic Acid | [Molecular Formula]
C26H28N2O6 | [MOL File]
851884-87-2.mol | [Molecular Weight]
464.51 |
| Hazard Information | Back Directory | [Uses]
6-[[3-[(1S)-2-Methoxy-1-methylethoxy]-5-[(1S)-1-methyl-2-phenylethoxy]benzoyl]amino]-3-pyridinecarboxylic Acid, is one of the glucokinase activator derivatives. GKAs activate GK via binding to an allosteric site of the enzyme. They increase glucose-stimulated insulin secretion and decrease blood glucose levels. Also, glucokinase activator GKA50 is shown to be able to promote proliferation by increasing the cell volume and thus, preventing apoptosis in rat pancreatic insulinoma-1 beta cell. | [storage]
Store at -20°C |
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