| Identification | Back Directory | [Name]
BREVETOXIN PBTX-3 | [CAS]
85079-48-7 | [Synonyms]
PBTX-3
toxint-17
Gb 3 toxin
BREVETOXIN3
PUMILIOTOXIN
brevetoxint17
BREVETOXIN PBTX-3
DIHYDROBREVETOXIN B
BKMHDYJRAAJTAD-RXUQWMQDSA-N
42-Deoxo-42-hydroxybrevetoxin B
42-Hydroxy-42-deoxobrevetoxin B
Brevetoxin B, 42-deoxo-42-hydroxy-
BREVETOXIN PBTX-3, PTYCHODISCUS BREVIS
Brevetoxin PbTx-3, Ptychodiscus brevis - CAS 85079-48-7 - Calbiochem | [Molecular Formula]
C50H72O14 | [MDL Number]
MFCD00214096 | [MOL File]
85079-48-7.mol | [Molecular Weight]
897.1 |
| Chemical Properties | Back Directory | [density ]
1.190±0.06 g/cm3(Predicted) | [storage temp. ]
-20C | [solubility ]
DMSO: soluble,Ethanol: soluble,Methanol: soluble | [form ]
Solid | [pka]
13.78±0.70(Predicted) | [color ]
White to off-white |
| Safety Data | Back Directory | [RIDADR ]
3172 | [RTECS ]
XW5885000 | [HazardClass ]
6.1(a) | [PackingGroup ]
I | [Safety Profile]
A poison by ingestion,
intraperitoneal, and intravenous routes.
When heated to decomposition it emits
acrid smoke and irritating vapors. |
| Hazard Information | Back Directory | [General Description]
Lipid-soluble polyether marine toxin produced by the red tide dinoflagellate, Ptychodiscus brevis, found along the Gulf Coast of Florida. Voltage-dependent Na+ channel activator that causes contractile paralysis in animal models by binding to a unique site on these channels. The excitatory action of brevetoxins on nerve and muscle membranes is responsible for a wide spectrum of the toxic effects, including massive transmitter release from nerve endings, muscle fasciculations, and ventricular fibrillation. The toxin does not bind to either tetrodotoxin or aconitine/veratridine sites. | [Biochem/physiol Actions]
Primary TargetVoltage-dependent Na+ channel activator |
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