| Identification | Back Directory | [Name]
Acelarin | [CAS]
840506-29-8 | [Synonyms]
Acelarin
NUC-1031
NUC-1031 impurity
Acelarin（NUC1031）
NUC-1031; NUC1031; NUC 1031
N-(2'-Deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl)-L-alanine phenylmethyl ester
N-(2'-Deoxy-2',2'-difluorocytidine 5'-P-phenyl phosphate) L-alanine benzyl ester
L-Alanine, N-(2'-deoxy-2',2'-difluoro-P-phenyl-5'-cytidylyl)-, phenylmethyl ester | [Molecular Formula]
C25H27F2N4O8P | [MDL Number]
MFCD27987942 | [MOL File]
840506-29-8.mol | [Molecular Weight]
580.47 |
| Chemical Properties | Back Directory | [Boiling point ]
708.4±70.0 °C(Predicted) | [density ]
1.51±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 12 mg/mL; DMSO: 14 mg/mL; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL; Ethanol: 10 mg/mL | [form ]
A crystalline solid | [pka]
11.46±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Acelarin is a phosphoramidate transformation of the pancreatic and ovarian cancer chemotherapy Gemcitabine; and the first anti-cancer ProTide to enter the clinic. | [storage]
Store at -20°C |
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