| Identification | Back Directory | [Name]
ARG-LYS-ARG-ALA-ARG-LYS-GLU | [CAS]
82801-73-8 | [Synonyms]
RKRARKE
PKG INHIBITOR
PKG Inhibitor，RKRARKE
PROTEIN KINASE G INHIBITOR
ARG-LYS-ARG-ALA-ARG-LYS-GLU
[ALA32]-HISTONE H2B (29-35)
OUKSKNTVYYVIMZ-DUJSLOSMSA-N
Alg-Lys-Arg-Ala-Arg-Lys-Glu
H-ARG-LYS-ARG-ALA-ARG-LYS-GLU-OH
ARG-LYS-ARG-ALA-ARG-LYS-GLU: RKRARKE
CGMP DEPENDENT KINASE INHIBITOR PEPTIDE
cGMP-Dependent Protein Kinase Inhibitor Peptide
arginyl-lysyl-arginyl-alanyl-arginyl-lysyl-glutamic acid
L-Glutamic acid, L-arginyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-L-lysyl- | [Molecular Formula]
C38H74N18O10 | [MDL Number]
MFCD00080098 | [MOL File]
82801-73-8.mol | [Molecular Weight]
943.11 |
| Chemical Properties | Back Directory | [density ]
1.50±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Solid | [pka]
3.16±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
Soluble in water at 1mg/ml |
| Hazard Information | Back Directory | [Description]
PKG inhibitor is a specific cGMP-dependent PKG inhibitor (Ki = 86 μM). This synthetic peptide is a nonphosphorylatable analog of a substrate corresponding to the serine-32 phosphorylation site in histone H2B. PKG inhibitor has been reported to block cGMP-dependent NMDA potentiation and nitric oxide-induced depression of GABA currents in cultured retinal amacrine cells. | [Uses]
A reversible substrate competitive inhibitor for protein kinase G. The sequence corresponds to a non-phosphorylatable analog of histone H2B. | [storage]
Store at -20°C |
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| Company Name: |
BOC Sciences
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| Website: |
https://www.bocsci.com |
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