Identification | Back Directory | [Name]
N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu | [CAS]
81279-39-2 | [Synonyms]
5'-DMT-2'-TBDMS-iBu-rG 5'-O-DMT-2'-O-TBDMS-ibu-rG 5'-O-DMT-2'-O-TBDMS-N2-ibu-rG 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine 5'-O-DMT-2'-OTBDMS-N-isobutyryl-Guanosine 5'-O-DMT-N-isobutyryl-2'-O-TBDMS-guanosine 5'-O-DMT-2'-O-(tertbutyldimethylsilyl)-N-isobutyryl-Guanosine 2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N-isobutyryl-guanosine 5-O-(4,4-Dimethoxytrityl)-2-O-(tertbutyldimethylsilyl)-N-isobutyryl-Guanosine N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(tert-butyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-[(1,1-diMethylethyl)diMethylsilyl]-N-(2-Methyl-1-oxopropyl)-Guanosine Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)- N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxyoxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide N-(9-((2R,3R,4R,5R)-5-((Bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-3-((tert-butyldiMethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyraMide | [EINECS(EC#)]
2017-001-1 | [Molecular Formula]
C41H51N5O8Si | [MDL Number]
MFCD00080293 | [MOL File]
81279-39-2.mol | [Molecular Weight]
769.96 |
Chemical Properties | Back Directory | [density ]
1.25 | [storage temp. ]
2-8°C | [form ]
Solid | [pka]
9.16±0.20(Predicted) | [color ]
White to light yellow | [InChIKey]
JMCNKJFOIJGYRG-HVXBIEPNNA-N | [SMILES]
O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](O[Si](C(C)(C)C)(C)C)[C@@H]1O |&1:25,27,44,53,r| |
Hazard Information | Back Directory | [Uses]
5''-O-DMT-2''-O-iBu-N-Bz-Guanosine (cas# 81279-39-2) is a nucleotide used in the preparation of 4''-C-methoxy-2''-deoxy-2''-fluoro modified ribonucleotides to improve metabolic stability and elicit efficient RNAi-mediated gene silencing. | [storage]
4°C, protect from light |
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