Identification | Back Directory | [Name]
LATHOSTEROL | [CAS]
80-99-9 | [Synonyms]
LATHOSTEROL γ-Cholestenol GAMMA-CHOLESTENOL Cholest-7-en-3-ol gamma-cholesterol DELTA7-Cholestenol 7-En-3-cholestanol 5A-cholest-7-en-3B-ol 5α-cholest-7-en-3β-ol 7-Cholesten-3-beta-ol delta(Sup7)-Cholestenol (3β,5α)-Cholest-7-en-3-ol 3β-hydroxy-5α,7-cholestene 3β-Hydroxy-5α-cholest-7-ene Cholest-7-en-3-ol, (3β,5α)- 5ALPHA-CHOLEST-7-EN-3BETA-OL 7,(5-ALPHA)-CHOLESTEN-3-BETA-OL 5Α-CHOLEST-7-EN-3-OL;LATHOSTEROL 3BETA-HYDROXY-5ALPHA,7-CHOLESTENE (3-beta,5-alpha)-cholest-7-en-3-o 3beta-Hydroxy-5alpha-cholest-7-ene Cholest-7-en-3-ol, (3beta,5alpha)- 3β-Hydroxy-5α,7-cholestene, Lathosterol 10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol (3S,5S,9R,10S,13R,14R,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol | [Molecular Formula]
C27H46O | [MDL Number]
MFCD00056176 | [MOL File]
80-99-9.mol | [Molecular Weight]
386.65 |
Chemical Properties | Back Directory | [Melting point ]
126°C | [Boiling point ]
452.8°C (rough estimate) | [density ]
0.9610 (rough estimate) | [refractive index ]
1.5250 (estimate) | [storage temp. ]
-20°C | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated) | [form ]
Solid | [color ]
White to Off-White |
Hazard Information | Back Directory | [Uses]
A Cholesterol (C432501) metabolite. Lathosterol (indicating cholesterol synthesis) and Sitosterol (indicating cholesterol absorption) also decreased with deteriorating health. Low Lathosterol, Sitosterol (S497050), and Cholesterol (C432501) predicted mortality additively and independently of each other. | [Definition]
ChEBI: A cholestanoid that is (5alpha)-cholest-7-ene substituted by a beta-hydroxy group at position 3. | [General Description]
Lathosterol is a cholesterol synthesis precursor. | [Biochem/physiol Actions]
5α-Cholest-7-en-3β-ol (Lathosterol) is an intermediate in cholesterol biosynthesis pathway. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol. | [storage]
Store at -20°C |
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