| Identification | Back Directory | [Name]
isoaminile | [CAS]
77-51-0 | [Synonyms]
TAT-1
MCT10
Aprecon
Dimyril
SLC16A10
Nullatuss
isoaminile
Isoaminilo
Brn 2849321
Einecs 201-033-5
28416-66-2 (Citrate)
isoaminile USP/EP/BP
Monocarboxylate transporter 10
3-cyano-5-dimethylamino-2-methyl-3-phenylhexane
4-dimethylamino-2-isopropyl-2-phenylvaleronitrile
4-Dimethylamino-2-isopropyl-2-phenylpentanenitrile
ANTI-SLC16A10 (C-TERM) antibody produced in rabbit
4-(dimethylamino)-2-phenyl-2-propan-2-ylpentanenitrile
Benzeneacetonitrile, α-[2-(dimethylamino)propyl]-α-(1-methylethyl)-
Benzeneacetonitrile, alpha-(2-(dimethylamino)propyl)-alpha-(1-methylethyl)-
4-dimethylamino-2-phenyl-2-propan-2-yl-pentanenitrile: 2-hydroxypropan e-1,2,3-tricarboxylic acid | [EINECS(EC#)]
201-033-5 | [Molecular Formula]
C16H24N2 | [MOL File]
77-51-0.mol | [Molecular Weight]
244.38 |
| Chemical Properties | Back Directory | [Boiling point ]
bp3 138-146° | [density ]
1.0080 (rough estimate) | [refractive index ]
1.5519 (estimate) | [storage temp. ]
-196°C | [form ]
buffered aqueous solution | [pka]
9.02±0.50(Predicted) |
| Hazard Information | Back Directory | [Originator]
Peracon,Toyo Jozo,Japan,1969 | [Uses]
Treatment of rheumatoid arthritis. | [Definition]
ChEBI: Isoaminile is an alkylbenzene. | [Manufacturing Process]
140 cc of benzene and 24 g of α-isopropyl phenyl acetonitrile are added to 7.5
g of sodium amide. The mixture is stirred and refluxed for one hour. After
cooling, 25 g of 2-dimethylamino-1-chloropropane, dissolved in 20 cc of
benzene, are added and stirring and refluxing of the mixture is continued for
4 hours. After the reaction is completed, water is added to the reaction
mixture. The benzene layer is separated from the aqueous layer and is
extracted by means of 4N hydrochloric acid. The acid solution is rendered
alkaline.
The separated oil is taken up in ether. After drying the ethereal solution over
sodium sulfate and distilling off the ether, the resulting crude α-isopropyl-α- (β'-dimethylamino propyl) phenyl acetonitrile is purified by distillation in a
vacuum. The compound boils at 138° to 146°C/3 mm, according to US Patent
2,934,557. | [Therapeutic Function]
Antitussive |
|
|