Identification | Back Directory | [Name]
rac-7-hydroxy Propranolol (hydrochloride) | [CAS]
76275-67-7 | [Synonyms]
7-Hydroxy Propranolol HCl 7-Hydroxypropranolol hydrochloride rac-7-hydroxy Propranolol (hydrochloride) 8-(2-Hydroxy-3-(isopropylamino)propoxy)naphthalen-2-ol hydrochloride | [Molecular Formula]
C16H22ClNO3 | [MDL Number]
MFCD32661440 | [MOL File]
76275-67-7.mol | [Molecular Weight]
311.804 |
Hazard Information | Back Directory | [Description]
rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of (±)-propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol).1 It also demonstrates potent vasodilator activity (0.20 potency relative to propranolol; pA2 = 7.58). | [References]
1. Oatis, J.E., Jr., Russell, M.P., Knapp, D.R., et al. Ring-hydroxylated propranolol: Synthesis and β-receptor antagonist and vasodilating activities of the seven isomers J. Med. Chem. 24(3),309-314(1981). |
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Company Name: |
BOC Sciences
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Website: |
www.bocsci.com |
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