| Identification | Back Directory | [Name]
6-Chloro-2,3,4,5-tetrahydro-1-(3-methylphenyl)-3-(2-propen-1-yl)-1H-3-Benzazepine-7,8-diol hydrobromide | [CAS]
74115-10-9 | [Synonyms]
SKF83822 hydrobromide,SKF-83822 hydrobromide
N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide
6-Chloro-2,3,4,5-tetrahydro-1-(3-methylphenyl)-3-(2-propen-1-yl)-1H-3-Benzazepine-7,8-diol hydrobromide | [Molecular Formula]
C20H23BrClNO2 | [MDL Number]
MFCD07773055 | [MOL File]
74115-10-9.mol | [Molecular Weight]
424.759 |
| Hazard Information | Back Directory | [Uses]
SKF 83822 Hydrobromide is a potent agonist of peripheral dopamine receptors. | [Definition]
ChEBI: A hydrobromide salt prepared from N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol and one equivalent of hydrogen bromide. High affinity, selective dopamine D1-like receptor agonist. Ki values are 3.2, 3.1, 1
6, 66, 335, 1167, 1251 and 1385 nM at recombinant D1, D5, D2, D3, D4, 5-HT2A, alpha1A and alpha1B receptors respectively. Stimulates adenylyl cyclase (EC50 = 65 nM) but not phosphoinositide hydrolysis. Induces extreme arousal
nd hyperlocomotion following subcutaneous administration in monkeys. | [storage]
Store at RT |
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| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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