| Identification | Back Directory | [Name]
BPV(HOPIC) | [CAS]
722494-26-0 | [Synonyms]
BPV(HOPIC)
K2[VO(O2)2C6H4NO3]
Bisperoxovanadium(HOpic)
bpV(HOpic) (potassium salt)
bpV(HOpic) (potassium salt, technical grade)
DIPOTASSIUM BISPEROXO(5-HYDROXYPYRIDINE-2-CARBOXYL)OXOVANADATE (V) | [Molecular Formula]
C6H4K2NO8V | [MDL Number]
MFCD01862576 | [MOL File]
722494-26-0.mol | [Molecular Weight]
347.24 |
| Hazard Information | Back Directory | [Uses]
bpV(HOpic) has been used in pharmacological perturbation of cell migration related signaling pathway. | [Biochem/physiol Actions]
bpV(OHpic) is a bisperoxovanadium inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(HOpic) are 14 nM for PTEN compared to 4.9 μM for PTPβ and 25.3 μM for PTP-1β. bpV(HOpic) has been shown to enhance PI3K/Akt signaling that could prevent myocardium from ischemia-reperfusion injury. |
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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BOC Sciences
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16314854226 |
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www.bocsci.com |
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