| Identification | Back Directory | [Name]
MASTOPARAN X | [CAS]
72093-22-2 | [Synonyms]
MP-X
MP-X
MASTOPARAN X
INWKGIAAMAKKLL-NH2
ILE-ASN-TRP-LYS-GLY-ILE-ALA-ALA-MET-ALA-LYS-LYS-LEU-LEU-NH2
H-ILE-ASN-TRP-LYS-GLY-ILE-ALA-ALA-MET-ALA-LYS-LYS-LEU-LEU-NH2 | [Molecular Formula]
C73H126N20O15S | [MDL Number]
MFCD00076866 | [MOL File]
72093-22-2.mol | [Molecular Weight]
1555.97 |
| Chemical Properties | Back Directory | [Boiling point ]
1797.4±65.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [storage temp. ]
-15°C | [form ]
Lyophilized solid. | [pka]
13.24±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Has effects similar to mastoparan; binds with high affinity to calmodulin and inhibits sarcoplasmic reticulum calcium-ATPase | [Definition]
ChEBI: Mastoparan-V is a member of the class of mastopyrans that is a 14-amino acid polypeptide comprising isoleucyl, asparaginyl, tryptophyl, lysyl, glycyl, isoleucyl, alanyl, alanyl, methionyl, alanyl, lysyl, lysyl, leucyl, and leucinamide residues coupled in sequence. It is the major active component of the venom of the hornet Vespa velutina and causes degranulation of mast cells. It exhibits antimicrobial activity against both Gram-positive and -negative bacteria as well as haemolytic activity on chicken, human and sheep erythrocytes. It has a role as an antibacterial agent. It is a member of mastoparans and a peptidyl amide. |
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