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ChemicalBook--->CAS DataBase List--->7181-73-9

7181-73-9

7181-73-9 Structure

7181-73-9 Structure
IdentificationBack Directory
[Name]

benzyldimethyl(2-phenoxyethyl)ammonium
[CAS]

7181-73-9
[Synonyms]

benzyldimethyl(2-phenoxyethyl)ammonium
N,N-Dimethyl-N-(2-phenoxyethyl)benzenemethanaminium
[EINECS(EC#)]

230-546-7
[Molecular Formula]

C17H22NO+
[MOL File]

7181-73-9.mol
[Molecular Weight]

256.363
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
Safety DataBack Directory
[Hazardous Substances Data]

7181-73-9(Hazardous Substances Data)
Hazard InformationBack Directory
[Originator]

Alcopar,Wellcome,UK,1960
[Definition]

ChEBI: Bephenium is an aromatic amine.
[Manufacturing Process]

First, dimethylamino-2-phenoxyethanewas made by reacting chloro-2- phenoxyethane with dimethylamine. Benzyl chloride (10 grams) was then added to a solution of 1-dimethylamino-2-phenoxyethane (12.3 grams) in acetone (35 ml). The mixture warmed spontaneously and N-benzyl-N,Ndimethyl-N-2-phenoxyethylammonium chloride slowly crystallized. After 24 hours, this solid was filtered off, washed with fresh acetone and dried immediately in vacuo, MP 135°-136°C.
2-Hydroxy-3-naphthoic acid (1.88 grams) was dissolved in hot aqueous sodium hydroxide (0.5N; 20 ml) and the resulting solution was slowly added to a solution of N-benzyl-N,N-dimethyl-N-2-phenoxyethylammonium chloride (2.9 grams) in water (5 ml). A gum separated at first but it solidified on scratching. After the addition was complete, the mixture was allowed to stand at room temperature for 2 hours and then filtered. The residue was washed with water and dried in vacuo to give N-benzyl-N,N-dimethyl-N-2- phenoxyethylammonium 2-hydroxy-3-naphthoate, MP 170°-171°C.
[Therapeutic Function]

Anthelmintic
[storage]

Store at -20°C
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