| Identification | Back Directory | [Name]
(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE | [CAS]
71636-61-8 | [Synonyms]
sk&f81297
(±)-6-Chloro-PB
SKF 81297 hydrobromi
SKF 81297 HYDROBROMIDE
(+/-)-SKF-81297 HYDROBROMIDE
(+/-)-6-CHLORO-PB HYDROBROMIDE
(+-)-6-CHLORO-PB HYDROBROMIDE (+-)-SKF-8 1297, HCL
2,3,4,5-Tetrahydro-6-chloro-1-phenyl-1H-3-benzazepine-7,8-diol
6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol
6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-
6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepinehydrobromide
6-CHLORO-2,3,4,5-TETRAHYDRO-1-PHENYL-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE
(+/-)-6-CHLORO-7,8-DIHYDROXY-1-PHENYL-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINE HYDROBROMIDE
(±)-SKF-81297 hydrobromide, (±)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide | [Molecular Formula]
C16H17BrClNO2 | [MDL Number]
MFCD00153782 | [MOL File]
71636-61-8.mol | [Molecular Weight]
370.67 |
| Hazard Information | Back Directory | [Uses]
(±)-6-Chloro-PB hydrobromide has been used as a dopamine D1 receptor (Drd1a) agonist to study the role of the drd1a-dopamine receptor inactivation of extracellular signal?regulated protein kinase 1/2 (ERK1/2) in the wild-type and striatum of dopamine-depleted mice. It has also been used as a Drd1a agonist to identify the contribution of D1 (D1R)-like dopamine receptor signaling on learning and memory in Barnes maze in rats. | [Definition]
ChEBI:9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol is a benzazepine. | [Biological Activity]
Dopamine D 1 -like receptor agonist. Centrally active following systemic administration in vivo . | [Biochem/physiol Actions]
(+/-)-6-Chloro-PB HBr is a full D1 dopamine receptor agonist. |
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