| Identification | Back Directory | [Name]
trans-Tranilast | [CAS]
70806-55-2 | [Synonyms]
trans-Tranilast
Tranilast (trans-)
trans-Tranilast, >98%
Tranilast Impurity 3 (trans-Tranilast)
2-(3,4-Dimethoxycinnamoylamino)benzoic acid
2-(3,4-Dimethoxy-trans-cinnamoylamino)benzoic acid
2-[[(2E)-3-(3,4-DiMethoxyphenyl)-1-oxo-2-propen-1-yl]aMino]benzoic Acid
Benzoic acid, 2-[[(2E)-3-(3,4-dimethoxyphenyl)-1-oxo-2-propen-1-yl]amino]-
3-{2-[4-(6-FLUORO-1,2-BENZOXAZOL-3-YL)-1-PIPERIDINYL]ETHYL}-2-METHYL-7,8-DIHYDRO-4H-PYRIDO[1,2-A]PYRIMIDINE-4,9(6H)-DIONE | [Molecular Formula]
C18H17NO5 | [MDL Number]
MFCD00864787 | [MOL File]
70806-55-2.mol | [Molecular Weight]
327.33 |
| Chemical Properties | Back Directory | [Melting point ]
184 °C(Solv: water (7732-18-5); acetone (67-64-1)) | [Boiling point ]
585.6±50.0 °C(Predicted) | [density ]
1.299±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO: 100 mg/mL (305.50 mM) | [form ]
Solid | [pka]
3.45±0.36(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
trans-Tranilast is used to treat bronchial asthma, allergic rhinitis and atopic dermatitis.
| [Definition]
ChEBI: Tranilast is an amidobenzoic acid that is anthranilic acid in which one of the anilino hydrogens is replaced by a 3,4-dimethoxycinnamoyl group. It has a role as an anti-asthmatic drug, a nephroprotective agent, an anti-allergic agent, a calcium channel blocker, an antineoplastic agent, an aryl hydrocarbon receptor agonist and a hepatoprotective agent. It is a member of cinnamamides, a dimethoxybenzene, an amidobenzoic acid and a secondary carboxamide. It is functionally related to an anthranilic acid. |
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