| Identification | Back Directory | [Name]
2,3-DIHYDROXY-4-METHOXYACETOPHENONE | [CAS]
708-53-2 | [Synonyms]
NSC 46636
2,3-Dihydroxy-4-Methoxyacetohpe
GALLACETOPHENONE-4-METHYL ETHER
Gallacetophenonemonomethylether
GALLACETOPHENONE-4'-METHYL ETHER
Gallacetophenone 4-O-methyl ether
4-METHOXY-2,3-DIHYDROXYACETOPHENONE
2,3-DIHYDROXY-4-METHOXYACETOPHENONE
2,3-Dihydroxy-4-methoxyacetohpenone
Dihydroxymethoxyacetohpenonehydrate
2',3'-DIHYDROXY-4'-METHOXYACETOPHENONE
1-(2,3-DIHYDROXY-4-METHOXYPHENYL)ETHANONE
2',3'-DIHYDROXY-4'-METHOXYACETOHPENONE, HYDRATE | [Molecular Formula]
C9H10O4 | [MDL Number]
MFCD00016685 | [MOL File]
708-53-2.mol | [Molecular Weight]
182.17 |
| Chemical Properties | Back Directory | [Melting point ]
133 °C | [Boiling point ]
359.6±42.0 °C(Predicted) | [density ]
1.284±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [form ]
powder to crystal | [pka]
8.98±0.15(Predicted) | [color ]
Light yellow to Yellow to Green |
| Hazard Information | Back Directory | [Uses]
1-(2,3-Dihydroxy-4-methoxyphenyl)ethanone is a a neuroprotective compound isolated from Cynenchum paniculatum. It exerts neuroprotective and cognitive-enhancing activities through its antioxidant activity and may be helpful for the treatment of Alzheimer''s disease. | [Preparation]
Preparation by reaction of acetic acid on pyrogallol 1-methyl ether, ? with zinc chloride at reflux (155–160°) (Nencki reaction); ? with boron trifluoride on a steam bath (77%). | [in vivo]
2,3-dihydroxy-4-methoxyacetophenone (50mg/kg; po) improves the impairment of spatial memory induced by scopolamine[1]. |
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