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5α-Cholanic Acid-3,6-dione is a secondary bile acid.1 Levels of 5α-cholanic acid-3,6-dione are decreased in the large intestinal contents of germ-free mice. | [References]
1. Dempsey, J.L., Wang, D., Siginir, G., et al. Pharmacological activation of PXR and CAR downregulates distinct bile acid-metabolizing intestinal bacteria and alters bile acid homeostasis Toxicol. Sci. 168(1),40-60(2019). |
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