Identification | Back Directory | [Name]
1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE | [CAS]
688348-33-6 | [Synonyms]
CAY10465 CAY10465 Exclusive CAY10465;CAY-10465;CAY 10465 1,3-DICHLORO-5-[(1E)-2(4-TRIFLUOROMETHYLPHENYL)ETHENYL]-BENZENE 1,3-dichloro-5-{(E)-2-[4-(trifluoromethyl)phenyl]ethenyl}benzene | [Molecular Formula]
C15H9Cl2F3 | [MDL Number]
MFCD08062182 | [MOL File]
688348-33-6.mol | [Molecular Weight]
317.13 |
Chemical Properties | Back Directory | [Boiling point ]
361.2±42.0 °C(Predicted) | [density ]
1.378±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2)(1:1): .5 mg/ml; Ethanol: 20 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white |
Hazard Information | Back Directory | [Description]
The aryl hydrocarbon receptor (AhR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin, benzo[a]pyrene, and numerous polyaromatics from soot and coal tar. CAY10465 is an analog of resveratrol acting as a potent and selective AhR agonist, with a Ki of 0.2 nM. CAY10465 is inactive as a ligand for the estrogen receptor even at 100 μM. | [Uses]
(E)-1-[4-(Trifluoromethyl)phenyl]-2-(3,5-dichlorophenyl)ethene is a stilbene derivative of resveratrol and a selective aryl hydrocarbon receptor agonist. | [storage]
Store at -20°C |
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DC Chemicals
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