| Identification | Back Directory | [Name]
PINOCEMBRIN | [CAS]
68745-38-0 | [Synonyms]
NSC 43318
PINOCEMBRIN
(±)-Pinocchio
DL-Pinocembrin
rac-PinoceMbrin
(+/-)-Pinocembrin
5,7-DIHYDROXYFLAVANONE
Pinocembrin racemate (DL0108)
5,7-DIHYDROXY-3'4'5'-FLAVANONE
5,7-Dihydroxy-2-phenyl-4-chromanone
5,7-DIHYDROXY-2-PHENYL-CHROMAN-4-ONE
5,7-Dihydroxyflavanone (Pinocembrin)
5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one
2-Phenyl-5,7-dihydroxy-3,4-dihydro-2H-1-benzopyran-4-one
5,7-Dihydroxy-2,3-dihydro-2-phenyl-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-
(2R)-5,7-dihydroxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one | [Molecular Formula]
C15H12O4 | [MDL Number]
MFCD00017482 | [MOL File]
68745-38-0.mol | [Molecular Weight]
256.25 |
| Chemical Properties | Back Directory | [Melting point ]
202-203°C | [Boiling point ]
511.1±50.0 °C(Predicted) | [density ]
1.386±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly, heated), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
7.50±0.40(Predicted) | [color ]
White to Pale Beige |
| Hazard Information | Back Directory | [Uses]
Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c. |
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