| Identification | Back Directory | [Name]
Trichostatin C | [CAS]
68676-88-0 | [Synonyms]
145-A
7-[4-(Dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-2,4-heptadienamide
2,4-Heptadienamide, 7-[4-(dimethylamino)phenyl]-N-(β-D-glucopyranosyloxy)-4,6-dimethyl-7-oxo-, (2E,4E,6R)-
7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide
(2E,4E)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide
(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-4,6-dimethyl-7-oxo-N-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhepta-2,4-dienamide | [Molecular Formula]
C23H32N2O8 | [MDL Number]
MFCD08061903 | [MOL File]
68676-88-0.mol | [Molecular Weight]
464.51 |
| Chemical Properties | Back Directory | [Melting point ]
171-173° | [alpha ]
D24 +50.5 ±0.9° (c = 0.987 in methanol) | [density ]
1.33±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | [form ]
White to off-white powder. | [pka]
12.85±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Trichostatin C is an inducer of erythroid differentiation and histone H4 acetylation level. | [Uses]
Trichostatin C is the first example of a glucopyranosyl hydroxamate from nature. The conjugation may act to protect the less stable N-OH group of Trichostatin A. Trichostatin C displays antifungal, antiprotozoan and antitumour activity, albeit less potent than trichostatin A | [Definition]
ChEBI: Trichostatin C is a trichostatin and an O-amino sugar. It is functionally related to a trichostatin A. |
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