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ChemicalBook--->CAS DataBase List--->68353-55-9

68353-55-9

68353-55-9 Structure

68353-55-9 Structure
IdentificationBack Directory
[Name]

7-O-DeMethyl α-Narcotine
[CAS]

68353-55-9
[Synonyms]

Noscapine Impurity 1
7-O-Demethyl a-Narcotine
7-O-DeMethyl α-Narcotine
1(3H)-Isobenzofuranone, 7-hydroxy-6-methoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, (3S)-
[Molecular Formula]

C21H21NO7
[MDL Number]

MFCD12031407
[MOL File]

68353-55-9.mol
[Molecular Weight]

399.39
Chemical PropertiesBack Directory
[Melting point ]

> 158°C (dec.)
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

Dichloromethane (Slightly), DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

White to Pale Yellow
Hazard InformationBack Directory
[Uses]

7-O-Demethyl α-Narcotine, is a derivative of Narcotine (N378890), a noscapinoid class of microtubule binding compounds that alter microtubule dynamics without affecting tubulin polymer mass. Noscapinoids show great promise as chemotherapeutic agents for the treatment of human cancers. Unlike Narcotine, (-)-α-Narcotinediol deos not inhibit small-intestinal transport in rats.
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