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ChemicalBook--->CAS DataBase List--->677773-32-9

677773-32-9

677773-32-9 Structure

677773-32-9 Structure
IdentificationBack Directory
[Name]

Etamicastat HCl salt
[CAS]

677773-32-9
[Synonyms]

Etamicastat HCl salt
BIA 5-453 hydrochloride
Etamicastat hydrochloride
[Molecular Formula]

C14H16ClF2N3OS
[MDL Number]

MFCD32173149
[MOL File]

677773-32-9.mol
[Molecular Weight]

347.81
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Light yellow to yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H319
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P
Hazard InformationBack Directory
[Description]

Etamicastat, also known as BIA 5-453, is a potent, reversible, peripherally selective dopamine β-hydroxylase inhibitor (DBH inhibitor). Chronic dopamine ?-hydroxylase inhibition with etamicastat effectively decreases blood pressure, although does not prevent the development of hypertension in the spontaneously hypertensive rat.
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