| Identification | Back Directory | [Name]
4-(3-FLUORO-BENZYLOXY)-BENZALDEHYDE | [CAS]
66742-57-2 | [Synonyms]
Safinamide Intermediate 1
Safinamide mesylate Intermediate
Safinamide mesylate
Intermediate 1
4-(3-Fluorobenzyloxy)benzaldehyde >
4-[(3-fluorophenyl)methoxy]-Benzaldehyde
Benzaldehyde, 4-[(3 -fluorophenyl)Methoxy]-
4-(3-FLUORO-BENZYLOXY)-BENZALDEHYDE
Intermediate 1
4-(3-FLUORO-BENZYLOXY)-BENZALDEHYDE ISO 9001：2015 REACH
4-(3-Fluoro-benzyloxy)benzaldehyde, 4-(3-Fluoro- benzyloxy)benzaldehyde | [EINECS(EC#)]
613-982-6 | [Molecular Formula]
C14H11FO2 | [MDL Number]
MFCD02605317 | [MOL File]
66742-57-2.mol | [Molecular Weight]
230.23 |
| Chemical Properties | Back Directory | [Melting point ]
46.0 to 50.0 °C | [Boiling point ]
265°C/3mmHg(lit.) | [density ]
1.211±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
soluble in Methanol | [form ]
Solid:crystalline | [color ]
White to Almost white | [CAS DataBase Reference]
66742-57-2 |
| Hazard Information | Back Directory | [Uses]
4-(3-Fluorobenzyloxy)benzaldehyde is useful for organic reactions and synthesis. | [Synthesis]
4-(3-fluoro-benzyloxy)-benzaldehyde is synthesized by the reaction of 4-Hydroxybenzaldehyde with 3-fluorobenzyl bromide. 4-Hydroxybenzaldehyde, 3-fluorobenzyl bromide, potassium carbonate, and acetone were sequentially added to a single-neck round bottom flask. Reaction at 60 ° C for 5 h. Cool to room temperature, filter, and collect the filtrate.Purification by direct column chromatography. 4-(3-fluoro-benzyloxy)-benzaldehyde was obtained as a white solid (1.78 g, 94.4%).
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