| Identification | Back Directory | [Name]
1',2'-dihydrorotenone | [CAS]
6659-45-6 | [Synonyms]
NSC 53866
NSC 351138
Dihydrorotenone
1',2'-dihydrorotenone
dihydrorotenone standard
2R,6aS,12aS-2-isopropyl-8,9-dimethoxy-1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one
(2R)-1,2,12,12aα-Tetrahydro-2α-isopropyl-8,9-dimethoxy[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aαH)-one
(2R,6aS,12aS)-1,2,12,12a-Tetrahydro-8,9-dimethoxy-2-(1-methylethyl)-[1]benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one
[1]Benzopyrano[3,4-b]furo[2,3-h][1]benzopyran-6(6aH)-one, 1,2,12,12a-tetrahydro-8,9-dimethoxy-2-(1-methylethyl)-, (2R,6aS,12aS)- | [Molecular Formula]
C23H24O6 | [MDL Number]
MFCD01662620 | [MOL File]
6659-45-6.mol | [Molecular Weight]
396.43 |
| Chemical Properties | Back Directory | [Melting point ]
216℃ | [Boiling point ]
553.9±50.0 °C(Predicted) | [density ]
1.251±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white | [EPA Substance Registry System]
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| Hazard Information | Back Directory | [Uses]
Dihydrorotenone, a natural pesticide, is a potent mitochondrial inhibitor. Dihydrorotenone probably induces Parkinsonian syndrome. Dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway[1]. | [storage]
Store at -20°C | [References]
[1] Zhang J, et al. The natural pesticide dihydrorotenone induces human plasma cell apoptosis by triggering endoplasmic reticulum stress and activating p38 signaling pathway. PLoS One. 2013 Jul 26;8(7):e69911. DOI:10.1371/journal.pone.0069911 |
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