Identification | Back Directory | [Name]
STROPHANTHIDIN | [CAS]
66-28-4 | [Synonyms]
corchorin cynotoxin nsc-86078 Corcholin cyanotoxin cymarigenin CYMARIGENEN Corchotoxin apocynamarin corchorgenin corchsularin erysimupikron Corchorogenin Strophantidin erysimupicrone STROPHANTHIDIN antibioticxs-89 strophanthidine K-STROPHANTHIDIN STROPHANTHIDIN K STIGMASTANOL(SH) convallatoxigenin k-strophanthidine 20(22)-cardenolide corchosideaaglycon 3β,5,14-Trihydroxy-19-oxo-5β 5-beta-hydroxy-19-oxodigitoxigenin 3,5,14-trihydroxy-19-oxocard-20(22)-enolide 3-beta,5,14-trioxy-19-oxo-digen-(20:22)-olid 3-beta,5,14-trioxy-19-oxo-carden-(20:22)-olid 19-oxo-cardogenen-(20:22)-triol-(3-beta,5,14) 3β5,14-Trihydroxy-19-oxo-5β20(22)-cardenolide 5BETA,20[22]-CARDENOLIDE-19-ONE-3BETA,5,14-TRIOL 3BETA,5,14-TRIHYDROXY-19-OXO-5BETA,20[22]-CARDENOLIDE 3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolid 3-beta,5,14-trihydroxy-19-oxo-5-beta-card-20(22)-enolide (3beta,5beta)-3,5,14-trihydroxy-19-oxocard-20(22)-enolide 3,5,14-trihydroxy-19-oxo-,(3-beta,5-beta)-card-20(22)-enolid 3β,5,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide, Cymarigenen, K-Strophanthidin Strophanthidin,3β,5,14-Trihydroxy-19-oxo-5β,20(22)-cardenolide, Cymarigenen, K-Strophanthidin (3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde (3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-17-(5-keto-2H-furan-3-yl)-13-methyl-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde | [EINECS(EC#)]
200-626-6 | [Molecular Formula]
C23H32O6 | [MDL Number]
MFCD00046266 | [MOL File]
66-28-4.mol | [Molecular Weight]
404.5 |
Chemical Properties | Back Directory | [Melting point ]
169°C | [alpha ]
D25 +43.1° (c = 2.8 in methanol) | [Boiling point ]
446.1°C (rough estimate) | [density ]
1.432±0.06 g/cm3 (20 ºC 760 Torr) | [refractive index ]
1.4593 (estimate) | [storage temp. ]
−20°C
| [solubility ]
ethanol: complete50mg/mL, clear, colorless to yellow | [form ]
Solid | [pka]
13.92±0.70(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
cardiotonic | [Definition]
ChEBI: Strophanthidin is a 3beta-hydroxy steroid, a 14beta-hydroxy steroid, a 5beta-hydroxy steroid, a 19-oxo steroid, a member of cardenolides and a steroid aldehyde. It is functionally related to a 5beta-cardanolide. | [General Description]
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG | [Biochem/physiol Actions]
Strophanthidin is a cardiotonic steroid that elevates the activity of Na+/K+-ATPase in cardiac myocytes.1 It decreases the potassium content and raises the sodium content in rabbit renal cortex slices.2 |
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