| Identification | Back Directory | [Name]
3-benzyl-6-bromo-2-chloroquinoline | [CAS]
654655-68-2 | [Synonyms]
Bedaquiline Impurity B
3-benzyl-6-bromo-2-chloroquinoline
6-Bromo-2-chloro-3-(phenylmethyl)quinoline
Quinoline, 6-bromo-2-chloro-3-(phenylmethyl)- | [Molecular Formula]
C16H11BrClN | [MDL Number]
MFCD22493487 | [MOL File]
654655-68-2.mol | [Molecular Weight]
332.62 |
| Chemical Properties | Back Directory | [Melting point ]
111-112℃ | [Boiling point ]
435.9±40.0 °C(Predicted) | [density ]
1.482±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,2-8°C | [pka]
-0.42±0.50(Predicted) |
| Hazard Information | Back Directory | [Uses]
3-Benzyl-6-bromo-2-chloroquinoline is an intermediate in the synthesis of (αS,βR)-Bedaquiline (B119540), which is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis. |
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