| Identification | Back Directory | [Name]
MT-DADMe-ImmA | [CAS]
653592-04-2 | [Synonyms]
MTDIA
MT-DADMe-ImmA HCl
Methylthio-DADMe-Immucillin A
METHYLTHIO-DADME-IMMUCILLIN A; MTDIA
MTDIA; MTDIA HCL; METHYLTHIO-DADME-IMMUCILLIN A; MT-DADME-IMMA; MT-DADME-IMMA HCL
3-Pyrrolidinol, 1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(methylthio)methyl]-, (3R,4S)- | [Molecular Formula]
C13H19N5OS | [MOL File]
653592-04-2.mol | [Molecular Weight]
293.39 |
| Chemical Properties | Back Directory | [Melting point ]
108-110 °C | [Boiling point ]
566.1±50.0 °C(Predicted) | [density ]
1.412±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 10 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml | [form ]
A crystalline solid | [pka]
14.13±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
MT-DADMe-ImmA is an inhibitor of 5''-methylthioadenosine phosphorylase (MTAP; Ki = 1.7 nM). It increases levels of MTA , a product of polyamine metabolism, in FaDu human squamous cell carcinoma cells when used at a concentration of 1 μM. MT-DADMe-ImmA (5, 9, and 21 mg/kg per day for 28 days) reduces tumor growth in a FaDu mouse xenograft model. | [storage]
Store at -20°C |
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| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
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