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ChemicalBook--->CAS DataBase List--->651005-90-2

651005-90-2

651005-90-2 Structure

651005-90-2 Structure
IdentificationBack Directory
[Name]

2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
[CAS]

651005-90-2
[Synonyms]

Jedi2
2-Methyl-5-(2-thienyl)-3-furancarboxylic acid
[Molecular Formula]

C10H8O3S
[MOL File]

651005-90-2.mol
[Molecular Weight]

208.23
Chemical PropertiesBack Directory
[Boiling point ]

356.9±42.0 °C(Predicted)
[density ]

1.336±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

powder
[pka]

4.38±0.26(Predicted)
[color ]

White
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H317-H319
[Precautionary statements ]

P261-P264-P280-P280-P333+P313-P337+P313
[HS Code ]

2932190090
Hazard InformationBack Directory
[Definition]

ChEBI: 2-Methyl-5-(2-thienyl)-3-furoic acid is a furoic acid.
[Biological Activity]

Jedi2 is an activator of the mechanosensitive Piezo1 channel th at binds at a different place from Yoda1. It exhibits long-range allosteric gatingactivating Piezo1 through the extracellular side of its peripheral blade-like structure rather than the C-terminal extracellular domain of the pore.
[storage]

Store at -20°C
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