Identification | Back Directory | [Name]
L-ISOGLUTAMINE | [CAS]
636-65-7 | [Synonyms]
Glu-NH2 L-Glu-NH2 H-GLU-NH2 H-ISOGLN-OH H-L-Glu-NH2 H-GLU-NH2 HCL L-ISOGLUTAMINE GLUTAMIC ACID-NH2 L-GLUTAMIC ACID AMIDE L-Glutamic acid α-amide L-GLUTAMIC ACID ALPHA-AMIDE H-Isogln-OH, L-IsoglutaMine L-ISOGLUTAMINE HYDROCHLORIDE 3-(Carboxymethyl)alaninamide (4S)-4,5-diamino-5-oxopentanoicaci (S)-4,5-Diamino-5-oxopentanoic acid (4S)-4,5-diamino-5-oxopentanoic acid (4S)-4-amino-4-carbamoylbutanoic acid L-Glutamic acid alpha-amide USP/EP/BP Pentanoic acid, 4,5-diamino-5-oxo-, (4S)- L-GLUTAMIC ACID ALPHA-AMIDE HYDROCHLORIDE L-Glutamic acid α-amide≥ 98% (Assay by Titration) | [Molecular Formula]
C5H10N2O3 | [MDL Number]
MFCD00135661 | [MOL File]
636-65-7.mol | [Molecular Weight]
146.14 |
Chemical Properties | Back Directory | [Melting point ]
160 °C | [alpha ]
D21 +20.5° (c = 6.1 in H2O) | [Boiling point ]
423.1±40.0 °C(Predicted) | [density ]
1.321±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
Water (Sparingly) | [form ]
Solid | [pka]
pK1 3.81; pK2 7.88(at 25℃) | [color ]
White to Off-White |
Hazard Information | Back Directory | [Chemical Properties]
White to off-white powder | [Definition]
ChEBI: L-isoglutamine is an isoglutamine that has L-configuration. It is an isoglutamine and a L-glutamic acid derivative. It is an enantiomer of a D-isoglutamine. |
Questions And Answer | Back Directory | [Preparation]
N-CBZ-γ-benzyl-L-isoglutamine (5 gm.) was dissolved in 100 ml. of 50% ethanol and hydrogenated for 12 hr. at room temperature and atmospheric pressure in the presence of palladium catalyst (5% Pd on calcium carbonate). The catalyst was filtered off and a trace of calcium ions was removed with oxalic acid. The solution was evaporated to dryness, the residue dissolved in a small amount of hot water, and the solution treated with charcoal. Alcohol was added to the cloud point and L-isoglutamine was recovered from the chilled solution as fine white crystals, m.p. 186-188°, yield 65%. |
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Company Name: |
INTATRADE GmbH
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Tel: |
+49 3493/605464 |
Website: |
www.intatrade.de |
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