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ChemicalBook--->CAS DataBase List--->633370-23-7

633370-23-7

633370-23-7 Structure

633370-23-7 Structure
IdentificationBack Directory
[Name]

Lapatinib impurity P
[CAS]

633370-23-7
[Synonyms]

Deschloro Lapatinib
Lapatinib impurity P
Lapatinib Deschloro Impurity
N-(4-((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine
4-Quinazolinamine, N-[4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-
[Molecular Formula]

C29H27FN4O4S
[MOL File]

633370-23-7.mol
[Molecular Weight]

546.61
Chemical PropertiesBack Directory
[Boiling point ]

740.7±60.0 °C(Predicted)
[density ]

1.337±0.06 g/cm3(Predicted)
[pka]

6.34±0.19(Predicted)
Hazard InformationBack Directory
[Uses]

Deschloro Lapatinib is dechlorinated analogue of drug Lapatinib (L175808), which is a selective inhibitor of epidermal growth factor receptor (EGFR) and HER-2 tyrosine kinases. Lapatinib is used to treat breast cancer, especially metastatic breast cancer that has progressed after trastuzumab treatment and other chemotherapy.
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