| Identification | Back Directory | [Name]
isovaleryl coenzyme a lithium salt hydrate | [CAS]
6244-91-3 | [Synonyms]
IV-CoA
Isovaleryl-CoA
3-Methylbutyryl-CoA
isovaleryl-coenzyme A
Coenzyme A, S-(3-methylbutanoate)
isovaleryl coenzyme a lithium salt hydrate
[5-(6-aminopurin-9-yl)-4-hydroxy-2-[[hydroxy-[hydroxy-[3-hydroxy-2,2-dimethyl-3-[2-[2-(3-methylbutanoylsulfanyl)ethylcarbamoyl]ethylcarbamoyl]propoxy]-phosphoryl]oxy-phosphoryl]oxymethyl]oxolan-3-yl]oxyphosphonic acid | [Molecular Formula]
C26H44N7O17P3S | [MOL File]
6244-91-3.mol | [Molecular Weight]
851.65 |
| Hazard Information | Back Directory | [Uses]
Isovaleryl coenzyme A (IV-CoA ) lithium salt hydrate may be used:
- as substrate for β-Hydroxy-β-methylbutyric acid synthesis in cell-free extracts from G. reessii
- in high-performance liquid chromatography (HPLC) for the characterization of IV-CoA from lymphocytes
- as a substrate in isovaleryl-CoA dehydrogenase assay
| [Definition]
ChEBI: A methylbutanoyl-CoA is the S-isovaleryl derivative of coenzyme A. | [General Description]
Isovaleryl coenzyme A, an intermediate of the leucine catabolism. It is synthesized from β-methylbutyric acid by the action of enzyme acyl CoA synthetase. The conversion of isovaleryl-CoA to methylcrotonyl-CoA is catalyzed by the enzyme isovaleryl-CoA dehydrogenase in leucine catabolism pathway. The enzyme isovaleryl-CoA oxidase also calalyzes this conversion in fatty acid β-oxidation pathway. |
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Sigma-Aldrich
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